Academic and Professional Achievements

Research Interest

Cancer Biology, Cell Science and Environmental Biotechnology.

Awards / Scholarship / Fellowships

1. CSIR – Senior Research Fellowship
2. Govt. of Karnataka, Vidyasiri Scholarship
3. DST-PURSE Technical assistant fellowship

Patent

• IBAM-Mineral Water Quality Testing System: IoT-Based Automatic Mineral Water Quality Testing and Management System. Inventors: P Shiva Keshava Kumar, Santhosh B M, Prakash K K, D P Nagarajappa, Manjunatha S, Pavan K J, Gurumurthy D M, G C Manjunath, Naveen Kumar M, Kiran Kumar K M, Babu R L, Manjunatha Gowda K S. Indian Patent Application No: 202041051636 A, dated 11/12/2020.    

Book Chapters Published

1. Biradar S., Kiran Kumar K.M., Naveen Kumar M., Babu R.L. (2020) Identification of Clinical Variants Present in Skin Melanoma Using Exome Sequencing Data. In: Jyothi S., Mamatha D., Satapathy S., Raju K., Favorskaya M. (eds) Advances in Computational and Bio-Engineering. CBE 2019. Learning and Analytics in Intelligent Systems, vol 16. Springer, Cham. pp 85-96.

2. Naveen Kumar. M., Shivaleela Biradar and Babu R.L. (2020) Chapter-13: Cell Signalling and apoptosis in animals in “Advances in Animal Genomics” edited by Sukanta Mondal and Ram Lakhan Singh. Elsevier Inc. https://doi.org/10.1016/B978-0-12-820595-2.00013-8.

Peer-Reviewed Scientific Publications

1. Sharanraj V., C. M. Ramesha, Kavya K, Vasantha Kumar, Sadashiva M., Chandan B. R.,              Naveen Kumar M. (2020) Zirconia: as a biocompatible biomaterial used in Dental implants. Advances in Applied Ceramics: Structural, Functional and Bioceramics. https://doi.org/10.1080/17436753.2020.1865094.
2. Babu R.L., Naveen Kumar M., Rajeshwari H. Patil, Kiran Kumar K. M., Devaraju, K.S, Govindarajan T. Ramesh, S. Chidananda Sharma (2019) Forskolin and Phorbol 12-myristate 13-acetate modulates the expression pattern of AP-1 factors and cell cycle regulators in estrogen-responsive MCF-7 cells. Genes and Diseases. 6(2): 159-166.
3. Naveen Kumar M., Babu R.L., Rajeshwari H. Patil, Kiran Kumar K. M., Shubha M. Hegde, Rashmi Nagesh, Kavya K., Govindarajan T. Ramesh, S. Chidananda Sharma, Srinivas C. (2019) Protein kinases orchestrate cell cycle regulators in differentiating BeWo choriocarcinoma cells. Molecular and cellular biochemistry. 452(1-2): 1–15.
4. Nagesh, R., K. K. Kumar, M. Naveen Kumar M., R. H. Patil and S. C. Sharma (2019). Stress activated p38 MAPK regulates cell cycle via AP-1 factors in areca extract exposed human lung epithelial cells. Cytotechnology, 71(2): 507-520.
5. Rashmi Nagesh, K. K. K. M., Naveen Kumar M., Manjunath K, S. Chidananda Sharma, and S. M. (2018). Oxidative stress induced G1/S phase cell cycle arrest and cellular apoptosis in cultured buccal KB epithelial cells on exposure of aqueous extract of areca nut. International Journal of Pharmacy and Biological Sciences. 8(3): 626-635.
6. Rajeshwari H Patil, Naveen Kumar M., Kiran Kumar K.M., Rashmi Nagesh, Kavya K., Babu R.L., Govindarajan T. Ramesh, and S. Chidananda Sharma. (2018) Dexamethasone inhibits inflammatory response via down regulation of AP-1 transcription factor in human lung epithelial cells, Gene, 645: 85-94.
7. Kavya Krishnappa, Naveen Kumar Mallesh, Srikantaradhya Chidananda Sharma, Doddamane Manjulakumari. (2017) Midostaurin inhibits hormone-refractory prostate cancer PC-3 cells by modulating nPKCs and AP-1 transcription factors and their target genes involved in cell cycle, Frontiers in Biology, 12(6): 421-429.
8. Shubha M. Hegde, Naveen Kumar M., Manjunath K, and S. Chidananda Sharma. (2017) Role of NF-kB transcription factors, cell-cycle regulators and apoptotic genes in proliferation of MCF-7 cells. International Journal of Pharma and Bio Sciences, 8(2): (B) 553-561.
9. Kavya K., Naveen Kumar M., Rajeshwari H Patil, Shubha M Hegde, Kiran Kumar K.M., Rashmi Nagesh, Babu R.L., Govindarajan T. Ramesh and S. Chidananda Sharma. (2017) Differential expression of AP-1 transcription factors in human prostate LNCaP and PC-3 cells: role of Fra-1 in transition to CRPC status. Molecular and cellular biochemistry, 433(1-2): 13-26.
10. Kiran Kumar K.M., Naveen Kumar M., Rashmi Nagesh, Rajeshwari H. Patil, Babu R.L., S. Chidananda Sharma, and M. K (2017). Arsenic induces oxidative stress and apoptosis in human lung cancer cells. International Journal of Life Sciences, 5(4): 551-560.
11. Rashmi Nagesh, Kiran Kumar K. M, Naveen Kumar. M, Rajeshwari Patil, Kavya K, Babu R L, Govindarajan T. Ramesh and S. Chidananda Sharma. (2017) Aqueous areca nut extract induces oxidative stress in human lung epithelial A549 cells: Probable role of p21 in inducing cell death. Gene Reports, 6: 103-111.
12. Kiran Kumar K. M, Naveen Kumar. M, Rajeshwari Patil, Rashmi Nagesh, Shubha M. Hegde, Kavya K, Babu R L, Govindarajan T. Ramesh and S. Chidananda Sharma. (2016) Cadmium induces oxidative stress and apoptosis in lung epithelial cells. Toxicology Mechanisms and Methods, 26(9): 658-666.
13. Shubha M. Hegde, Naveen Kumar. M, Kavya K, Kiran Kumar K. M, Rashmi Nagesh, Rajeshwari Patil, Babu R L, Govindarajan T. Ramesh and S. Chidananda Sharma. (2016) Interplay of nuclear receptors (ER, PR, and GR) and their steroid hormones in MCF-7 cells. Molecular and cellular Biochemistry, 422(1-2): 109-120.
14. Rajeshwari Patil, Babu R L, Naveen Kumar. M, Kiran Kumar K. M, Shubha M. Hegde, Rashmi Nagesh, Govindarajan T. Ramesh and S. Chidananda Sharma. (2015) Anti-inflammatory effect of apigenin on LPS induced pro-inflammatory mediators and AP-1 factors in human lung epithelial cells. Inflammation, 39(1): 138-147.
15. Rajeshwari Patil, Naveen Kumar. M, Babu R L., and S. Chidananda Sharma. (2015) Anti-inflammatory activity of Vitex negundo, Boswellia serrata and Aegle marmelos leaf extracts in LPS treated A549 cells. International Journal of Phytopharmacy, 5(2): 12-20.
16. Rajeshwari Patil, Babu R L, Naveen Kumar. M, Kiran Kumar K. M, Shubha M. Hegde, Govindarajan T. Ramesh and S. Chidananda Sharma. (2015) Apigenin inhibits PMA induced expression of mRNAs of pro-inflammatory cytokines and AP-1 factors in A549 cells. Molecular and cellular Biochemistry, 403(1-2): 95-106.
17. Shubha M. Hegde, Babu R L, Vijayalakshmi E, Rajeshwari Patil, Naveen Kumar. M, Kiran Kumar K. M, Rashmi Nagesh, Kavya K and S. Chidananda Sharma. (2015) Biosorption of hexavalent chromium from aqueous solution using chemically modified Spirulina platensis algal biomass: An ecofriendly approach. Desalination and Water Treatment, 57(18): 1–10.
18. Alurappa, R., M. R. M. Bojegowda, V. Kumar, Naveen Kumar M.,and S. Chowdappa (2014). Characterisation and bioactivity of oosporein produced by endophytic fungus Cochliobolus kusanoi isolated from Nerium oleander L. Natural product research, 28(23): 2217-2220.
19. Babu, R.L., Vijayalakshmi, E., Naveen Kumar. M., Patil, R.H., Devaraju, K.S., and Sharma, S.C. (2013) Biosorption of Chromium (VI) and Lead (II): Role of Spirulina platensis in the Treatment of Industrial Effluent. Bioremediation Journal, 17(4): 231-239.
20. Babu R L, Vijayalaksmi E, Naveen Kumar. M, Rajeshwari H. Patil and S. Chidananda Sharma. (2013) Blocking of CDK4 gene expression by antisense oligos induce apoptosis and decreases the proliferation of A549 cells. International Journal of Scientific Research, 2(8): 51-53.
21. Babu R.L, Naveen Kumar. M, Patil, R.H, Devaraju, K.S, Ramesh, G.T, and Sharma, S.C. (2013) Effect of estrogen and tamoxifen on the expression pattern of AP-1 factors in MCF-7 cells: role of c-Jun, c-Fos, and Fra-1 in cell cycle regulation. Molecular and cellular biochemistry, 380(1-2): 143-151.

Abstracts Published and Presented in the Conference Proceedings

1. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Glucocorticoid Receptor-mediated regulation of Activator Protein-1 transcription factors and cell cycle regulators in placental BeWo choriocarcinoma cells. “1^st International Conference on Life, Chemical, and Health Sciences”. Organized by the Ramaiah College of Arts, Science and Commerce, Bengaluru and Karnataka Science and Technology (KSTA), Department of Science and Technology, Govt. of Karnataka. Oral Presentation 24^th and 26^th October, 2019.
2. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Coleus forskohlii extract forskolin regulates the differentiation of human placental choriocarcinoma cells via cAMP-activated PKA cascade. “National Conference on Phytochemicals and Microbial Bioactive Compounds - Role in Agriculture and Human welfare”. Organized by the Department of Microbiology and Biotechnology, Bangalore University, Bengaluru. Oral Presentation 3^rd and 4^th October, 2019.
3. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Protein kinases regulate proliferation and differentiation of human placental cells. “11th Annual Conference of Karnataka Science and Technology Academy in association with NMKRV College for Women, Bengaluru on Theme ‘New Vistas in Science and Technology for Common Good’. Poster Presentation 1^st and 2^nd February 2019.
4. Naveen Kumar M., S. Chidananda Sharma and Srinivas C. Effects of Forskolin and PMA on the differentiation and cell cycle regulation of human placental choriocarcinoma cells. “National Conference on Science and Technology for inclusive development”. Organized by the Gulbarga University, Kalaburagi and Karnataka Science and Technology (KSTA), Department of Science and Technology, Govt. of Karnataka. Poster Presentation 6^th and 7^th March 2018.
5. Babu R L, Naveen Kumar M, Rajeshwari H Patil, Kiran Kumar K M, Govindarajan T Ramesh and S. Chidananda Sharma. Forskolin inhibits PMA induced expression of mRNAs of AP-1 factors (c-Jun/c-Fos and Fra1) in MCF-7 cells.  Antisense oligos of c-Jun and c-Fos inhibits the cell proliferation. “National conference on Cell mechanics and interactions at the physics biology interface”, Department of Physics and DST-PURSE Programme, Bangalore University, Bengaluru. Poster Presentation. 30^th and 31^st August 2013.

Faculty Development Programs

1. Faculty Development Program on “Influence of New Education Policy on Quality Parameters of HEI” Organized by IQAC, Ramaiah College of Arts, Science and Commerce, Bengaluru from 9^th to 13^th November 2020.
2. Online Faculty Development Program on “Online Teaching during COVID-19 pandemic” Organized by IQAC, Ramaiah College of Arts, Science and Commerce, Bengaluru from 23^rd to 27^th June 2020.
3. Faculty Development Program on” 2D and 3D Models of Cell Culture and their Applications” Organized by Department of Biotechnology, Chemical Engineering, Ramaiah Institute of Technology, Bengaluru from  17^th to 22^nd June 2019.

Workshops/ Seminars/ Symposiums – Attended

1. Science Academies Lecture Workshop on “Nanomaterials-Applications in Biotechnology” Organized by Dept. of Biotechnology, Ramaiah Institute of Technology, Bengaluru. 29^th and 30^th August 2019.
2. Symposium on “Healthy Life style and Human Welfare”, Organized by the UGC-CPEPA and Department of Zoology, Bangalore University, Bengaluru. 18^th and 19^th November 2014.
3. Indo-UK seminar on opportunities in Biotechnology, Organized by Department of Microbiology and Biotechnology, Bangalore University and British Council, Chennai. 28^th September 2013.
4. National workshop on “Application of Bioinformatics in medicine”, Organized by Department of Bioinformatics and Biotechnology, Akkamahadevi Women’s University, (KSWU), Bijapur, 586108. 8^th and 9^th January 2013.
5. National workshop on “Frontier in cell biology and Biotechnology” Department of Microbiology and Biotechnology and DST-PURSE Programme, Bangalore University, Bangalore. 28^th and 29^th December 2012.