Dr. Sathish Babu - Biotechnology

Name: Dr. Sathish Babu
Designation: Assistant Professor
Department: Department of Biotechnology & Genetics
Qualification: MSc, PhD(Germany)
Year of Joining: 2022
Work Experience: 15 years combined experience in industry and academia.
Subject Specialisation:Cell biology, molecular biology, Biotechnology.

RESEARCH

Thesis title: Role of MET in SV40-induced mammary tumorigenesis. Our laboratory generated and characterized a transgenic mouse model (WAP-T mice) suitable for molecular analysis of initiation and progression of mammary carcinoma.

I focused on the role of MET during SV40 induced tumorigenesis. My thesis concluded that p53 acts as a repressor of the MET gene. Alleviation of this repressor function by T-Ag is essential for T-Ag mediated cellular transformation. A novel role for p53 gene was identified.

PUBLICATIONS (PAPER, BOOKS, ARTICLES ETC):
  • Vimaleswaran KS, Radha V, Ramya K, Babu HN, Savitha N, Roopa V, Monalisa D, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians. Hum Genet.2008 Jul;123(6):599-605.2008 May 9.
  • Radha V, Vimaleswaran KS, Babu HN, Deepa R, Anjana M, Ghosh S, Majumder PP, Rao MR, Mohan V. Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians.Diabet Med. 2007 Apr;24(4):398-402. 2007 Feb 28.
  • Radha V, Vimaleswaran KS, Babu HN, Abate N, Chandalia M, Satija P, Grundy SM, Ghosh S, Majumder PP, Deepa R, Rao SM, Mohan V. Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.Diabetes Care. 2006 May;29(5):1046 51.
  • Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Babu HN, Deepa R, Rao MR, Mohan V. Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians. Diabet Med. 2005 Nov;22(11):1516-21.
MAJOR PROJECTS

Project Coordinator and Key Investigator for Gab2 project (RT-PCR based assay method of early detection and treatment of breast cancer) funded by SBIRI-BIRAC Department of Biotechnology. Govt of India.

 
Area of specialization

Cell biology, molecular biology, Biotechnology.

 
NATIONAL AND INTERNATIONAL SEMINARS, WORKSHOPS AND CONFERENECES
 
  • International Food Conference (IFFCON 2009) Mysore – Poster Presentation – Incidence of Yersina Enterocolitica in street food.
  • German Cancer Congress (2007) Berlin – Poster Presentation – Role of c-MET in mammary induced tumorigenesis.
CONTACT
  • Email:sathish_btech@msrcasc.edu.in
    Assistant Professor, Department of Biotechnology
  • Address: Department of Biotechnology & Genetics
    Bengaluru - 560054
    Karnataka, India